I would like to talk with you for a few minutes about non-surgical treatments for Peyronie’s disease. In this article, I’m going to define Peyronie’s disease, discuss some of the common misconceptions associated with Peyronie’s disease, and provide you with some examples of non-surgical treatment of this common condition.
Peyronie’s disease is defined as angulation or bending of the penis that results in pain during intercourse for the man and/or his partner. It is a common condition, and most men after middle-age have some element or component of Peyronie’s disease. 10% of men after a surgical removal of their prostate gland for prostate cancer will have Peyronie’s disease. Usually, this problem does not go away without treatment, and it usually worsens in half of the man with the condition. It’s a common cause of erectile dysfunction, and most men with an erectile dysfunction have some element of Peyronie’s disease.
In the past, there have been oral therapies consisting of either vitamin E, potaba, tamoxifen, omega-3 fatty acids. But they produce no benefit compared to a placebo or sugar pill. Consequently, those oral therapies are not recommended for Peyronie’s disease.
Now a drug that has been used for the peripheral vascular disease to increase the blood supply to a man, who has decreased in blood supply to their lower extremities, called trental has been reported to have one-third of the men have a positive response to this oral medication. Also, L-Arginine and phosphodiesterase inhibitors Viagra, Levitra, or Cialis increase the local levels of nitric oxide and can be associated with a decrease in the progression of the disease. There are topical treatments such as topical verapamil. However, no independent studies confirm its efficacy.
Shockwave that has been used for the destruction of kidney stones had been tried for the treatment of Peyronie’s disease with a weekly shockwave treatment for four weeks. Studies have reported no improvement, and interestingly enough some of the men, who received shockwave therapy, had been made worse.
There are injections, particularly injections of verapamil, that reduce the size and firmness of the plaque that is in the penis that is responsible for the curvature. To use verapamil, it requires an injection every two weeks for a total of 12 injections. Also, interferon injections head been reported to have a 25% improvement rate. Another injection is clostridial collagenase, which has been used in the treatment of Dupuytren’s contracture, which is a similar problem that occurs in hand and has been reported to have mild improvement in Peyronie’s disease. To use clostridial collagenase consists of two injections per week for 16 weeks with the likelihood of 30% improvement.
Lately, there has been the advent of penile stretch therapy that has been proposed by doctors Larry Levin from Chicago, Illinois. This is the application of a vacuum device placed over the penis twice a day for 12 days. Reports by doctor Levin indicate that nearly two-thirds of the men had improvement in the curvature and also approximately a half inch increase in the length of the penis. Penile traction therapy consisting of a device called FastSize, which was invented by Doctor Larry Levin from Chicago; it is worn on the penis that places and external traction on the penis. This device has to be worn for 2-8 hours per day for 8 months in order to achieve an improvement in the Peyronie’s disease.
The men, who do this, report decrease in curvature and an increase in the length of the penis by approximately 1 inch. Also, these men have reported an improvement in their erectile dysfunction. Again this technique or this treatment option it may be helpful to the highly motivated man with Peyronie’s disease, who is willing to comply with the treatment program.
In summary, Peyronie’s disease is a common condition that significantly impacts millions of American men. There are non-surgical options, and I suggest you see your urologists.